Intense brain cortical enhancement on CT in laminar necrosis verified by biopsy.

Anoxia of the cortical gray matter of the CNS may result from a variety of pathophysiologic conditions, including systemic hypoxemia, cerebral hypoperfusion, hypoglycemia, and carbon monoxide or cyanide poisoning . Areas of the brain with high metabolic demand or in boundary zones of perfusion are more vulnerable to tissue anoxia than other areas are [1] . The increased susceptibility of the cerebral cortex and the basal ganglia in CNS anoxia is seen at autopsy and can be identified on CT. We report a case of laminar necrosis of the cerebral cortex that was seen as intense, diffuse cortical enhancement on double-dose, delayed, contrast-enhanced CT, and was subsequently confirmed by biopsy.